「Bardoxolone methyl」熱門搜尋資訊

Bardoxolone methyl

「Bardoxolone methyl」文章包含有:「Bardoxolonemethyl」、「Bardoxolonemethyl(CDDO」、「Bardoxolonemethyl(RTA402,甲基巴多索隆)」、「BardoxoloneMethyl」、「Bardoxolonemethylanalogattenuatesproteinuria」、「BardoxoloneMethylandKidneyFunctioninCKDwithType...」、「BardoxoloneMethylinType2DiabetesandStage4...」、「Bardoxolonemethyl:Uses」、「FDARejectsBardoxoloneMethylForChronicKidney...」

查看更多
OmaveloxoloneReata Pharmaceuticals
Provide From Google
Bardoxolone methyl
Bardoxolone methyl

https://en.wikipedia.org

Bardoxolone methyl is an experimental and orally-bioavailable semi-synthetic triterpenoid, based on the scaffold of the natural product oleanolic acid.

Provide From Google
Bardoxolone methyl (CDDO
Bardoxolone methyl (CDDO

https://www.ncbi.nlm.nih.gov

As a multifunctional agent, CDDO-Me has improved the renal function in patients with chronic kidney disease associated with type 2 diabetes.

Provide From Google
Bardoxolone methyl (RTA 402,甲基巴多索隆)
Bardoxolone methyl (RTA 402,甲基巴多索隆)

https://www.medchemexpress.cn

Bardoxolone methyl (NSC 713200; RTA 402; CDDO Methyl ester) 是一种合成的三萜类化合物,具有潜在的抗肿瘤和抗炎活性,作为Nrf2 通路的激活剂和NF-κB 途径的抑制剂。

Provide From Google
Bardoxolone Methyl
Bardoxolone Methyl

https://www.sciencedirect.com

Bardoxolone methyl is a semisynthetic triterpene, which promotes antioxidant response and inhibits pro-inflammatory signals through activating nuclear factor ...

Provide From Google
Bardoxolone methyl analog attenuates proteinuria
Bardoxolone methyl analog attenuates proteinuria

https://pubmed.ncbi.nlm.nih.go

Multiple clinical studies have shown that bardoxolone methyl, a potent activator of nuclear factor erythroid 2-related factor 2 (Nrf2), is effective in ...

Provide From Google
Bardoxolone Methyl and Kidney Function in CKD with Type ...
Bardoxolone Methyl and Kidney Function in CKD with Type ...

https://www.nejm.org

Bardoxolone methyl, an oral antioxidant inflammation modulator, has shown efficacy in patients with CKD and type 2 diabetes in short-term ...

Provide From Google
Bardoxolone Methyl in Type 2 Diabetes and Stage 4 ...
Bardoxolone Methyl in Type 2 Diabetes and Stage 4 ...

https://www.nejm.org

Among patients with type 2 diabetes mellitus and stage 4 chronic kidney disease, bardoxolone methyl did not reduce the risk of ESRD or death ...

Provide From Google
Bardoxolone methyl: Uses
Bardoxolone methyl: Uses

https://go.drugbank.com

It is a novel targeted cancer therapy with a unique mechanism of action. It exploits fundamental physiological differences between cancerous and ...

Provide From Google
FDA Rejects Bardoxolone Methyl For Chronic Kidney ...
FDA Rejects Bardoxolone Methyl For Chronic Kidney ...

https://www.hcplive.com

The complete response letter from the FDA cited a lack of effectiveness in slowing the loss of kidney function in patients with Alport syndrome.